Similac® NeoSure® Ready to Use

SIMILAC^® NEOSURE^® READY TO USE

DHA- and ARA-enriched formula

For use as a breast milk substitute in preterm infants being discharged home. For breastfed preterm infants; supplementing with feedings of prepared post-discharge formula is recommended as a strategy for meeting additional nutrient requirements.¹ Term infant formula (such as Similac Pro-Advance®) can be introduced at the discretion of the health care professional; once the baby has achieved adequate catch-up growth. Some recommendations include: the use of a post-discharge formula should be “individualized to optimize the growth trajectory of the infant over the first year.”¹; use from 40 to 52 weeks post-conception ²; stopping at 4 to 6 months corrected age if all growth parameters are >25th percentile.³ For oral or tube feeding use. Use under medical supervision.

¹ American Academy of Pediatrics Committee on Nutrition. Nutritional Needs of the Preterm Infant. In: Kleinman RE, Greer FR, eds. Pediatric Nutrition. 7th ed. Elk Grove Village, IL: American Academy of Pediatrics; 2014:109-11.
² ESPGHAN Committee on Nutrition. J Pediatr Gastroenterol Nutr. 2006;42:596-603.
³ Bhatia J. J Perinatol. 2005;25(suppl 2):S15-6.

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Availability

Values listed are subject to change. Please refer to the product label or packaging for the most current ingredients, allergen and nutrient profile information.

LIST NUMBER

ITEM

6635813

Similac Neosure^®, Ready to Use; 59-mL plastic bottles; 48/case

Features

Hypercaloric formula (74 Cal/100 mL [22 Cal/30 mL]) with higher levels of protein, electrolytes, vitamins, and minerals per 100 Cal than standard term formula.
Exclusive blend of DHA, lutein, and natural vitamin E:^* - Results of a clinical study point to protective effects of lutein on preterm retinal health and maturation.⁴
Supports catch-up growth during the first year:⁵ increased calories for growth; 33% more protein^† to help meet higher protein requirements; approximately 35% more calcium and phosphorus^† to support baby's growing bones.
Peer-reviewed studies evaluating the use of preterm post-discharge formula compared to term infant formula in preterm infants have demonstrated: greater gains in weight, length, and head circumference compared to those fed term formula^‡; an increase in lean body mass rather than fat mass.^6,7
Approximately 25% of fat as medium chain triglycerides, an easily digested and well-absorbed fat source.⁸
Non-GMO.^§
Easy to digest.^¶
Gluten-free.
Kosher.
Halal.

PRECAUTIONS

Never use a microwave oven to warm formula; serious burns can result. Test temperature before feeding to avoid scalding the baby’s mouth.
Not for parenteral use.

^* RRR-alpha-tocopherol, the most bioactive form of vitamin E.

^† Compared to Similac Pro-Advance® (per 100 Cal).

^‡ Similac® Neosure® formulation used in this study may differ slightly from current Similac® Neosure® product.

^§ Ingredients not genetically engineered.

⁴ Rubin LP, et al. J Perinatol. 2012;32(6):418-24.

^¶ Similar to other infant formulas.

⁵ Carver JD, et al. Pediatrics. 2001;107:683-689.

⁶ Cooke RJ, et al. Pediatr Res. 2010;67:660-4.

⁷ Lucas A, et al. Pediatrics. 2001;108:703-11.

⁸ Duggan C, et al. Nutrition in Pediatrics: Standard and Specialized Enteral Formulas. BC Decker Inc. Hamilton. 2008.

Values listed are subject to change. Please refer to the product label or packaging for the most current ingredients, allergen and nutrient profile information.

Preparation

Directions for Use

Do not use if breakaway ring is missing or broken.
Use as directed by a health care professional.
Always wash hands thoroughly with soap and water when preparing infant feedings.
- Twist off cap.
- Twist on nipple and ring.
Once feeding begins, use within 1 hour or discard.
Avoid prolonged exposure of bottles to light.
Store unopened at room temperature. Avoid extreme temperatures.

Values listed are subject to change. Please refer to the product label or packaging for the most current ingredients, allergen and nutrient profile information.

Nutrition

Unflavored Ready to Use

Similac Neosure^®, Ready to Use; 59-mL plastic bottles; 48/case

Serving size: 100 mL

Value

Product Characteristics

Caloric Density (Cal/mL)
0.74

Protein (% of total energy)
11.2

Protein Source
Dry or evaporated skim milk, whey protein concentrate

Fat (% of total energy)
48.5

MCT oil (% of total fats)
24.3

Omega-6:Omega-3 Ratio
6.4:1

Fat Source
Soy oil, coconut oil, MCT oil, M. alpina oil, Schizochytrium sp. oil

Carbohydrate (% of total energy)
40.3

Carbohydrate Source
Corn syrup solids, lactose

Total Cal:g Nitrogen Ratio
226:1

Nonprotein Cal:g Nitrogen Ratio
200:1

Water (g/L)
840

Osmolality (mOsm/kg water)
250

Renal Solute Load (mOsm/L)
188

Amount per Serving

Nutrient Data

ENERGY, Cal (kJ)
74 (311)

Protein, g
2.1

Taurine, mg
4.5

Carnitine, mg
4

Fat, g
4.1

Linoleic Acid, g
0.558

Linolenic Acid, g
0.074

Arachidonic Acid (ARA), g
0.019

Docosahexaenoic Acid (DHA), g
0.013

Carbohydrate, g
7.5

Nucleotides, mg
7.2

Vitamins

Inositol, mg
26

Lutein, mg
0.0115

Vitamin A, IU
342

Vitamin D, IU
52

Vitamin E, IU
2.7

Vitamin K, mg
0.0083

Vitamin C, mg
11

Thiamine, mg
0.164

Riboflavin, mg
0.112

Niacin, mg
1.45

Vitamin B6, mg
0.074

Folic Acid, mg
0.019

Vitamin B12, mg
0.0003

Pantothenic Acid, mg
0.6

Biotin, mg
0.007

Choline, mg
12

Minerals

Sodium, mg
25

Potassium, mg
112

Chloride, mg
56

Calcium, mg
78

Phosphorus, mg
46

Magnesium, mg
7

Iron, mg
1.3

Zinc, mg
0.89

Iodine, mg
0.011

Copper, mg
0.089

Manganese, mg
0.007

Selenium, mg
0.0016

Values listed are subject to change. Please refer to the product label or packaging for the most current ingredients, allergen and nutrient profile information.

Ingredients

Unflavored Ready to Use

Similac Neosure^®, Ready to Use; 59-mL plastic bottles; 48/case

Water, Corn Syrup Solids, Dry or Evaporated Skim Milk, Soy Oil, Lactose, Coconut Oil, Whey Protein Concentrate, Modiﬁed Coconut and/or Palm Kernel Oils (Medium Chain Triglycerides), M. Alpina Oil (A Source Of ARA), Schizochytrium Sp. Oil (A Source of DHA), Monoglycerides, Soy Lecithin, M-Inositol, Carrageenan, Taurine, L-Carnitine, Cytidine 5'-Monophosphate, Disodium Guanosine 5'-Monophosphate, Disodium Uridine 5'-Monophosphate, Adenosine 5'-Monophosphate, Lutein, MINERALS (Potassium Citrate, Calcium Carbonate, Magnesium Chloride, Potassium Hydroxide, Tricalcium Phosphate, Sodium Chloride, Ferrous Sulphate, Zinc Sulphate, Copper Sulphate, Manganese Sulphate, Sodium Selenate, Potassium Iodide), VITAMINS (Ascorbic Acid, Choline Chloride, Choline Bitartrate, D-Alpha-Tocopheryl Acetate, Niacinamide, Calcium D-Pantothenate, Vitamin A Palmitate, Thiamine Chloride Hydrochloride, Riboflavin, Pyridoxine Hydrochloride, Folic Acid, Phylloquinone, D-Biotin, Beta-Carotene, Vitamin D3, Cyanocobalamin), and As Needed: Potassium Chloride, Potassium Phosphate Dibasic.

Contains: Milk, Soy.

Values listed are subject to change. Please refer to the product label or packaging for the most current ingredients, allergen and nutrient profile information.

Availability

Values listed are subject to change. Please refer to the product label or packaging for the most current ingredients, allergen and nutrient profile information.

LIST NUMBER

ITEM

6635813

Similac Neosure^®, Ready to Use; 59-mL plastic bottles; 48/case

Features

Hypercaloric formula (74 Cal/100 mL [22 Cal/30 mL]) with higher levels of protein, electrolytes, vitamins, and minerals per 100 Cal than standard term formula.
Exclusive blend of DHA, lutein, and natural vitamin E:^* - Results of a clinical study point to protective effects of lutein on preterm retinal health and maturation.⁴
Supports catch-up growth during the first year:⁵ increased calories for growth; 33% more protein^† to help meet higher protein requirements; approximately 35% more calcium and phosphorus^† to support baby's growing bones.
Peer-reviewed studies evaluating the use of preterm post-discharge formula compared to term infant formula in preterm infants have demonstrated: greater gains in weight, length, and head circumference compared to those fed term formula^‡; an increase in lean body mass rather than fat mass.^6,7
Approximately 25% of fat as medium chain triglycerides, an easily digested and well-absorbed fat source.⁸
Non-GMO.^§
Easy to digest.^¶
Gluten-free.
Kosher.
Halal.

PRECAUTIONS

Never use a microwave oven to warm formula; serious burns can result. Test temperature before feeding to avoid scalding the baby’s mouth.
Not for parenteral use.

^* RRR-alpha-tocopherol, the most bioactive form of vitamin E.

^† Compared to Similac Pro-Advance® (per 100 Cal).

^‡ Similac® Neosure® formulation used in this study may differ slightly from current Similac® Neosure® product.

^§ Ingredients not genetically engineered.

⁴ Rubin LP, et al. J Perinatol. 2012;32(6):418-24.

^¶ Similar to other infant formulas.

⁵ Carver JD, et al. Pediatrics. 2001;107:683-689.

⁶ Cooke RJ, et al. Pediatr Res. 2010;67:660-4.

⁷ Lucas A, et al. Pediatrics. 2001;108:703-11.

⁸ Duggan C, et al. Nutrition in Pediatrics: Standard and Specialized Enteral Formulas. BC Decker Inc. Hamilton. 2008.

Values listed are subject to change. Please refer to the product label or packaging for the most current ingredients, allergen and nutrient profile information.

Preparation

Do not use if breakaway ring is missing or broken.
Use as directed by a health care professional.
Always wash hands thoroughly with soap and water when preparing infant feedings.
- Twist off cap.
- Twist on nipple and ring.
Once feeding begins, use within 1 hour or discard.
Avoid prolonged exposure of bottles to light.
Store unopened at room temperature. Avoid extreme temperatures.

Values listed are subject to change. Please refer to the product label or packaging for the most current ingredients, allergen and nutrient profile information.

Nutrition

Unflavored Ready to Use

Similac Neosure^®, Ready to Use; 59-mL plastic bottles; 48/case

Serving size: 100 Cal

Value

Product Characteristics

Caloric Density (Cal/mL)
0.74

Protein (% of total energy)
11.2

Protein Source
Dry or evaporated skim milk, whey protein concentrate

Fat (% of total energy)
48.5

MCT oil (% of total fats)
24.3

Omega-6:Omega-3 Ratio
6.4:1

Fat Source
Soy oil, coconut oil, MCT oil, M. alpina oil, Schizochytrium sp. oil

Carbohydrate (% of total energy)
40.3

Carbohydrate Source
Corn syrup solids, lactose

Total Cal:g Nitrogen Ratio
226:1

Nonprotein Cal:g Nitrogen Ratio
200:1

Water (g/L)
840

Osmolality (mOsm/kg water)
250

Renal Solute Load (mOsm/L)
188

Amount per Serving

Nutrient Data

ENERGY, Cal (kJ)
100 (418)

Protein, g
2.8

Taurine, mg
6

Carnitine, mg
5.4

Fat, g
5.5

Linoleic Acid, g
0.75

Linolenic Acid, g
0.1

Arachidonic Acid (ARA), g
0.025

Docosahexaenoic Acid (DHA), g
0.017

Carbohydrate, g
10.1

Nucleotides, mg
9.7

Vitamins

Inositol, mg
35

Lutein, mg
0.0155

Vitamin A, IU
460

Vitamin D, IU
70

Vitamin E, IU
3.6

Vitamin K, mg
0.011

Vitamin C, mg
15

Thiamine, mg
0.22

Riboflavin, mg
0.15

Niacin, mg
1.95

Vitamin B6, mg
0.1

Folic Acid, mg
0.025

Vitamin B12, mg
0.0004

Pantothenic Acid, mg
0.8

Biotin, mg
0.009

Choline, mg
16

Minerals

Sodium, mg
33

Potassium, mg
150

Chloride, mg
75

Calcium, mg
105

Phosphorus, mg
62

Magnesium, mg
9

Iron, mg
1.8

Zinc, mg
1.2

Iodine, mg
0.015

Copper, mg
0.12

Manganese, mg
0.01

Selenium, mg
0.0021

Values listed are subject to change. Please refer to the product label or packaging for the most current ingredients, allergen and nutrient profile information.

Ingredients

Unflavored Ready to Use

Similac Neosure^®, Ready to Use; 59-mL plastic bottles; 48/case

Contains: Milk, Soy.

Values listed are subject to change. Please refer to the product label or packaging for the most current ingredients, allergen and nutrient profile information.